Symptoms
This problem occurs when a call is made from unmanaged code to managed code, including direct unmanaged-to-managed calls within a single DLL. For example, the problem may occur when MEC++/IJW is used in ASP.NET applications. In ASP.NET, various events can cause applications to be reloaded into a new AppDomain. If you are using MEC++ components and IJW in this application, you may receive an AppDomainUnloadException error message.
Resolution
As part of the implementation of IJW, when a managed DLL that you created by using the C++ compiler loads, the runtime creates thunks for transitions from unmanaged code to managed code. These thunks contain a reference to the AppDomain in which the DLL loads. The runtime does not re-create these thunks if the DLL loads again; also, the runtime does not update the reference when the original AppDomain unloads and the DLL loads in another AppDomain.
When the program performs a transition from unmanaged code to managed code, the program uses the outdated AppDomain reference to run the managed code. Even if the original AppDomain is still loaded, the code cannot access static fields because the fields are specific to the AppDomain.